What is Rapamycin AE27685
Rapamycin is a macrolide antibiotic that has been studied as a potential anticancer agent. It binds to FK506 binding proteins (FKBPs) to form a complex that inhibits mammalian targets of rapamycin (mTOR).
Rapamycin also blocks p70 S6 kinase activation by interleukin-2 and thereby inhibits proliferation of T cells. It induces differentiation of human pluripotent stem cells (hPSCs) to mesendoderm and blood progenitor cells.
How to order Rapamycin AE27685
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Technical Data
CAS No: [53123-88-9]
Synonyms: (-)-Rapamycin,Sirolimus
Product Code: AE27685
MDL No: MFCD00867594
Chemical Formula: C51H79NO13
Molecular Weight: 914.17 g/mol
Smiles: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
Melting Point: 184 °C
Long Term Storage: store at <-15°C, close container well, keep dry
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