Hit Chemics

Large-Scale Manufacturing

Increasing scale with quality and flexibility. Our team of highly experienced chemists, technicians and project managers deliver products for pharmaceutical, diagnostic, analytical and research purposes.

 

Complex Chemical Manufacture and Supply: Service for Your Scale and Speed

Whether you are starting at large-scale or moving on from our custom synthesis and smaller scale production, at Hit Chemics we have a range of facilities to manufacture, fill and store high quality chemical products at scales up to 10 Metric Tons. Following the acquisition of VIO Chemicals,
the Hit Chemic Group has enhanced its capabilities of manufacturing at a significantly larger scale through the flexibility service of trusted partnerships.  

Technology transfer and scale-up 

We develop chemical transformations to safe, robust, scalable, and reproducible manufacturing processes. With our flexible service offering,
we can transfer your existing manufacturing and analytical methods ready for a large-scale manufacturing batch or scale-up an existing manufacturing methodology. Our experts can also perform a full program of route scouting, optimization, scale-up and associated analytical development.
As  part of our integrated CDMO services, your project will then transition seamlessly to the chosen facility for mid-scale or large-scale manufacturing at ISO 9001:2015.

 

We regularly manufacture a wide range of chemical entities, being experts in carbohydrates, nucleosides, and working with controlled substances, dyes and other materials.

These have a range of product applications, including:

  • Carbohydrate-based drugs
  • Carbohydrate-based detergents
  • Antiviral nucleoside analogues
  • Substrates for detection of enzymatic activity
  • Food and environmental analytical compounds
  • Cosmetic ingredients
  • Nutraceutical ingredients

Manufacturing in Europe

We have three manufacturing sites in Europe for larger scale production at ISO 9001:2015, which are based in Geneva, Switzerland, Vienna, Austria and Bratislava, Slovakia. The facilities are modern with a flexible range of reactors sizes from 60 L up to 3000 L and equipped with cutting-edge instrumentation and highly qualified scientists to support our production and QC processes. Our flexible warehousing capabilities mean we can rapidly pack, store and ship large qualities of high-quality products.

 

Technologies

Through the network of our manufacturing partners, we provide access to a broad range of capabilities, technologies, and types of chemical reactions, including: 

  • Flow chemistry
  • Carbohydrates transformation
  • Condensation
  • Reduction & oxidation
  • Nitration
  • Acylation
  • Methylation (Me2SO4)
  • Cyanation (NaCN)
  • Esterification
  • Carbonylation
  • Friedel-Crafts reaction
  • Diazotization
  • Chlorination (Cl2, POCl3, SOCl2)
  • Bromination & fluorination
  • Grignard reaction
  • Reactions from -78 °C to 300 °C
  • High-pressure hydrogenation
  • Reactions in liquid NH3
  • Enzymatic processes for chiral products
  • Thin film distillation
  • High vacuum distillation
  • Addition & cycloaddition