What is DL-3-Hydroxybutyric acid sodium salt
The D-isomer of 3-hydroxybutyric acid (also termed β-hydroxybutyrate, βOHB) is an important ketone body in the metabolism of humans and animals. (Chemically speaking it is not a ketone but is simply converted into a ketone by dehydrogenase activity).
βOHB has been looked upon as a carrier of energy from the liver to peripheral tissues (heart and kidneys) during fasting and exercise. Historically, the association with diabetes and starvation have given the ketone bodies a morbid connotation.
Only more recently, βOHB is also recognized as a potentially powerful nutritional supplement and a signaling molecule.
Since D-3-hydroxybutyrate can supply a great deal of energy, it is added to the diet to treat a variety of diseases and to support a ketogenic diet, for example in the treatment of epilepsy or diabetes.
Newman and Verdin (2017) presented a model of how ketone bodies and βOHB in particular might turn off genes that otherwise accelerate aging.
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