What is MDPV Methylenedioxypyrovalerone Crystal C16H21NO3
Methylenedioxypyrovalerone (MDPV) is a powerful synthetic stimulant drug often sold as “bath salts”. It blocks dopamine and norepinephrine reuptake in the brain, producing intense euphoria, high energy, severe psychological distress, and a high risk of addiction and overdose.
Methylenedioxypyrovalerone (MDPV) is a stimulant of the cathinone class that acts as a norepinephrine–dopamine reuptake inhibitor (NDRI).
MDPV acts as a stimulant and has been reported to produce effects similar to those of cocaine, methylphenidate, and amphetamine.
The primary psychological effects have a duration of roughly 3 to 4 hours, with aftereffects such as tachycardia, hypertension, and mild stimulation lasting from 6 to 8 hours.
High doses have been observed to cause intense, prolonged panic attacks in stimulant-intolerant users, and there are anecdotal reports of psychosis from sleep withdrawal and addiction at higher doses or more frequent dosing intervals.It has also been repeatedly noted to induce irresistible cravings to re-administer.
Reported modalities of intake include oral consumption, insufflation, smoking, rectal and intravenous use. It is supposedly active at doses of 3 to 5 mg, with typical doses ranging between 5 and 20 mg.
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Long-term effects
The long-term effects of MDPV on humans have not been studied, but it has been reported that mice treated with MDPV during adolescence show reinforcing behavior patterns similar to cocaine that are higher than the control groups.
These behavioural changes are related to alterations of factor expression directly related to addiction. All this suggests an increased vulnerability to cocaine abuse.
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