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N-Acetyl-D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-Acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of acetylgalactosamine residues attached to the IgA O-linked glycans of Crohn’sdisease patients is significantly decreased, and strongly correlated with clinical activity.

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What is N-Acetyl-D-galactosamine

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-Acetyl group (Collins, 2006).

GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides.

The number of acetylgalactosamine residues attached to the IgA O-linked glycans of Crohn’sdisease patients is significantly decreased, and strongly correlated with clinical activity.

It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohn’s disease (Inoue, 2012).

How to order N-Acetyl-D-galactosamine

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Technical Data
CAS No: [1811-31-0]
Synonyms: GalNAc, 2-Acetamino-2-deoxy-a-D-galactopyranose, N-Acetylchondrosamine, Acetylgalactosamine, N-Acetylgalactosamine, Galactosamine
Product Code: MA04390
MDL No: MFCD00065372
Chemical Formula: C8H15NO6
Molecular Weight: 221.21 g/mol
Smiles: [C@H]([C@H]([C@H]([C@@H](CO)O)O)O)(NC(C)=O)C=O
Melting Point: 159 °C
Long Term Storage: store at 2°C – 8°C, close container well

1 review for Buy N-Acetyl-D-galactosamine Online

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