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What is Mephedrone 4-MMC

Mephedrone, also known as 4-methylmethcathinone, 4-MMC, or 4-methylephedrone, is a synthetic stimulant drug belonging to the amphetamine and cathinone classes. It is commonly referred to by slang names such as drone, M-CAT, white magic, meow meow, and bubble. Chemically, it is similar to the cathinone compounds found in the khat plant, native to eastern Africa.

Mephedrone is typically found in tablet or crystal form, and users may swallow, snort, or inject it. Its effects are similar to those of MDMA, amphetamines, and cocaine, producing euphoria and increased sociability.

Mephedrone is rapidly absorbed, with a half-life of about two hours, and is primarily metabolized by CYP2D6 enzymes. Its effects are dose-dependent. Side effects can include cardiovascular changes: 13  and anxiety.

Mephedrone was first synthesised in 1929 but remained relatively obscure until it was rediscovered around 1999–2000. At that time, it was legal to produce and possess in many countries. By 2000, mephedrone was available for sale on the Internet.

By 2008, law enforcement agencies had become aware of the substance, and by 2010, it had been reported in most European countries, with significant prevalence in the United Kingdom. Mephedrone was first made illegal in Israel in 2008, followed by Sweden later that year.

By 2010, many European countries had banned the substance, and in December of that year, the European Union ruled it illegal. In Australia, New Zealand, and the United States, it is considered an analog of other illegal drugs and can be controlled under laws similar to the US Federal Analog Act.

Users have reported that mephedrone causes euphoria, stimulation, an enhanced appreciation for music, an elevated mood, decreased hostility, improved mental function and mild sexual stimulation; these effects are similar to the effects of cocaine, amphetamines and MDMA, and last different lengths of time depending on the way the drug is taken.

Of 70 Dutch users of mephedrone, 58 described it as an overall pleasant experience, and 12 described it as an unpleasant experience. In a survey of UK users who had previously taken cocaine, most users found it produced a better-quality and longer-lasting high and was less addictive.

The users were also asked to compare the “risk”, and they answered that it was equal. A study of users in Northern Ireland found they did not equate the fact that mephedrone was legal with it being safe to use.

This was contrary to another study in New Zealand, where users of benzylpiperazine thought that because it was legal, it was safe.

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