What is Gamma-Butyrolactone GBL
Gamma-Butyrolactone (GBL) is a clear, hygroscopic industrial chemical solvent. Once ingested, the human body rapidly converts GBL into GHB (gamma-hydroxybutyrate). Because it acts as a potent central nervous system depressant, it carries severe risks of overdose, addiction, and toxicity, and is heavily restricted or illegal globally.
γ-Butyrolactone (GBL) or gamma-butyrolactone is an organic compound with the formula O=CO(CH2)3. It is a hygroscopic, colorless, water-miscible liquid with a pleasant odor. It is the simplest 4-carbon lactone. It is mainly used as an intermediate in the production of other chemicals, such as N-methyl-2-pyrrolidone.
In humans, GBL acts as a prodrug for gamma-hydroxybutyric acid (GHB) and is often used as a recreational drug. GHB acts as a central nervous system (CNS) depressant with effects similar to those of barbiturates.
GBL has been found in extracts from samples of unadulterated wines. This finding indicates that GBL is a naturally occurring component in some wines and may be present in similar products.
The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by GC/MS analysis.
GBL can be found in cheese flavorings but typically results in a content of 0.0002% GBL in the final foodstuff.
Gamma-Butyrolactone is used as a chemical solvent and a cleaning agent, for example in paint stripping or for cleaning graffiti.
Butyrolactone is a precursor to other chemicals. Reaction with methylamine gives NMP, and with ammonia gives pyrrolidone. It is also used as a solvent in lotions and some polymers.
2-Methyl-4-chlorophenoxybutyric acid is an herbicide produced from butyrolactone.
Butyrolactone, with its wide liquid range, chemical stability, and high dielectric constant, is used in electrolytic capacitors as the organic solvent.
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